Last season’s finalists led briefly in the early stages after Heung-Min Son scored but the Germans were quickly level through Joshua Kimmich on the quarter-hour.
Robert Lewandowski put the visitors in front on the stroke of half-time and there was a giant helping of salt applied to the Spurs wounds in the second period as former Arsenal man Serge Gnabry scored four of Bayern’s five goals in a breathtaking 35-minute spell.
Harry Kane netted from the spot on 61 minutes – cutting the arrears to 4-2 – but it was to be a miserable night for Mauricio Pochettino and Tottenham, for whom memories of their previous meeting with Bayern in 1983; a year they would win the UEFA Cup, became increasingly distant.
The atmosphere was brimming from the word go and Tottenham fired the crowd to fever pitch on 12 minutes when Son gave them the lead.
The South Korean had already spurned two chances when a casual pass from Corentin Tolisso gifted possession to Moussa Sissoko. He fed Son and his low shot was just too powerful for the fingers of Manuel Neuer.
If there was ever to be a false dawn, this was it.
A shot from Lewandowski was partially cleared but Kimmich was there to control, skip away from Sissoko and curl a dipping shot beyond Hugo Lloris into the corner of the net three minutes later.
Tottenham were well in the contest thereafter, and it was end to end stuff, until Lewandowski produced a brilliant turn and right-foot finish past Lloris from 20 yards with the interval in sight.
Gnabry made the key difference in the second half. He skipped away down the left on 53 minutes and Toby Alderweireld couldn’t halt his progress into the penalty box, where he blasted a low shot into the corner of the Tottenham net.
Barely had Spurs had time to absorb that blow when the former Gunner was able to apply a carbon-copy finish after taking a pass this time from Tolisso.
Kingsley Coman then clipped Danny Rose inside the area and, despite Bayern’s protests, the spot-kick was awarded. After a delay and a chat with VAR, the referee confirmed the penalty and Kane made no mistake from 12-yards.
The home side tried hard to get within one, and they had their chances, but it was that man Gnabry again that ended the resistance on 83 minutes.
This was pure route one, albeit after a long spell of Bayern possession, a punt forward from Tolisso seeing the winger race in behind the tormented Serge Aurier and again finish down low to Lloris’ left hand side.
Lewandowski made it six on 87 minutes, diverting the ball past Lloris with a deliberate finish after a subtle pass from Philippe Coutinho. A minute later and Gnabry shot home from 20-yards, the boos ringing the stadium as Tottenham slumped to their heaviest ever European loss.