Two sides battling for a top four spot in the Premier League meet on Sunday as Manchester United face Chelsea.
Ole Gunnar Solskjaer's men must win to keep their hopes of Champions League football alive after eight defeats in their last nine matches in all competitions.
Chelsea also need to win as they try to hold off Arsenal, who are just one point behind them in the race for fourth.
Neither side can afford to slip up but Chelsea do have a lifeline as they will have to win the Europa League to qualify for the Champions League.
Ander Herrera may, with the midfielder missing the last six games with a hamstring injury.
Midfielder Scott McTominay missed Wednesday's derby defeat after failing a fitness test and he remains a doubt along with defender Phil Jones.
Maurizio Sarri should be able to call upon Antonio Rudiger as he tries to shake off a knee injury.
The German hobbled out of the Blues' 2-0 league loss at Liverpool but is closing in on full fitness.
N'Golo Kante remains a doubt due to a rib injury suffered in Monday's 2-2 draw with Burnley, while Callum Hudson-Odoi is a long-term absentee after Achilles surgery.
In a clash between two teams who have been consistently coming up short, Manchester United take on Chelsea at Old Trafford.
Both teams are coming into this game out of form with the Blues failing to win any of their last two games and Manchester United picking up just two wins from nine games in all competitions.
Looking at the prices though, the recommendation has to be to back the visitors. Chelsea may not have set the world alight with their football however, at least they have managed to put the ball in the back of the net.
Chelsea have scored nine goals in their last five games across all competitions. Manchester United have only managed two in that same period of time.
Looking at the head to head record, it is clear that we shouldn’t expect a goal fest. Five from their last seven encounters have seen to under 2.5 goals bet land.
What’s more, Manchester United will be keen to keep their back door shut after conceding four against Everton, three against Barcelona and more recently, two against City.
With that in mind, that is the recommended bet in a fixture which doesn’t fill us with much hope.
Under 2.5 Goals – Evs bet365