bet365 match odds: West Ham 23/20, Draw 5/2, Newcastle 13/5
The Hammers lost 1-0 at Manchester City in midweek, ending a three-game unbeaten run, but they will be confident of getting back to winning ways on home soil.
Manuel Pellegrini's men are unbeaten in their last five matches at the London Stadium and have suffered just one home defeat from their last eight games in all competitions.
The Chilean tactician is set to welcome back Austria international Marko Arnautovic, who missed the loss to the Citizens due to illness, whilst defenders Aaron Cresswell and Arthur Masuaku are also fit again.
Mexican forward Javier Hernandez was an unused substitute for the clash with City and he is pushing for a start, whilst strike duo Andy Carroll and Lucas Perez are both hoping to be named in the starting XI.
Newcastle have managed to pull away from the relegation zone after back-to-back victories and a third straight victory would put the Magpies a step closer to retaining their top-flight status.
Rafael Benitez's side kept clean sheets in the wins over Huddersfield and Burnley, but they have failed to win any of their last five away league games and have tasted success just twice away from home in the PL this term.
Midfielder Jonjo Shelvey requested to play with the reserves on Friday night to improve his match fitness and is not expected to feature against the Hammers, whilst goalkeeper Rob Elliot and defender Ciaran Clark remain sidelined with respective back and knee injuries.
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